A genetic disorder that makes XY fetuses insensitive (unresponsive) to androgens (male hormones). Instead, they are born looking externally like normal girls. Internally, there is a short blind-pouch vagina and no uterus, fallopian tubes or ovaries. There are testes in the abdomen or the inguinal canal. The complete androgen insensitivity syndrome [..]

A genetic intersex condition that causes a fetus with male chromosomes to be unable to develop male sex organs, so it has a female anatomy at birth and throughout life. Usually raised as girls, individuals with AIS do not have reproductive organs, do not menstruate, are infertile, and usually have vaginas that are too shallow to allow vaginal inter [..]

Androgen Insensitivity Syndrome (AIS) is a genetic disorder that causes individuals who are genetically male (with an X and Y chromosome) to present with physical female characteristics or with a comb [..]

A syndrome caused by a mutation of the androgen receptor gene that renders tissues insensitive to androgenic hormones like testosterone. Affected XY individuals are phenotypic females, but they have internal testes and regressed internal genital structures. See Figure 12.16.

A disorder of Sexual Development transmitted as an X-linked recessive trait. These Patients have a Karyotype of 46,XY with end-organ resistance to androgen due to Mutations in the Androgen Receptor (R [..]

A disorder also known as complete Androgen Insensitivity Syndrome (CAIS). The 46,XY genetic male totally lacks androgen responsiveness in the target organs thus Exhibits a female Phenotype.

A disorder also known as partial Androgen Insensitivity Syndrome (PAIS). These Patients exhibit partial resistance to androgenic and metabolic effects of Testosterone.

Androgen insensitivity syndrome (AIS) is a syndrome where male infants are not responsive to androgens (testosterone). People with this syndrome are “genetically” male.